Synaptic Neurobiology
TEAM
Dr. Kwok-On Lai received his Bachelor degree of Biochemistry with First Class Honours from the University of Hong Kong. He then pursued M.Phil and Ph.D studies at the Hong Kong University of Science and Technology (HKUST) under the guidance of Prof. Nancy Ip. With the award of Croucher Foundation Fellowship, Dr. Lai performed postdoctoral research in the United States with Prof. Kelsey Martin at UCLA, where he used photoactivation and time-lapse imaging to study synapse-to-nucleus protein trafficking in neuron that underlies long-term synaptic plasticity.
Dr. Lai returned to Hong Kong and joined HKUST as Research Assistant Professor to investigate the role of protein phosphorylation in synaptic plasticity and memory formation. He then set up his own laboratory at the University of Hong Kong, where his team studies the interplay between intracellular transport, protein post-translational modification and synaptic function of neuron. His recent research includes the investigation of disease-associated genetic variations using human stem cell-derived neuron. Dr. Lai joined City University of Hong Kong in 2021.
Professional Roles
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Chair of the Symposium “Towards an understanding of how the cytoskeleton and intracellular transport are regulated for synapse development and plasticity”; the International Society for Neurochemistry (ISN) Annual Meeting 2022
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Associate Chair in the Gordon Research Seminar (GRS) in Molecular and Cellular Neurobiology “Exploring the Frontiers of Foundational and Translational Neuroscience”
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Editorial Board member of Scientific Reports and Frontiers in Molecular Neuroscience
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Lead Guest Editor for the Special Issue “Molecular Mechanisms of Dendritic Spine Development and Plasticity” in Neural Plasticity
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Ad-hoc reviewer for eLife, Cell Reports, Science Signaling, European Journal of Neuroscience
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Council member of the Asian-Pacific Society for Neurochemistry (APSN)
Current Members
Research Students
Research Staff
Alumni
Jonathan Hei-Lok Chan
MPhil student
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Leonard Cheung
Technical Officer
Now a Senior Technical Officer at the University of Hong Kong
Charles Lau
Research Assistant
Dr. Xuting Shen
Postdoctoral Fellow
Matthew Yip
Research Assistant
Now a Ph.D student at the Chinese University of Hong Kong
Ka Wing (Ben) Chan
Research Assistant
Now a Masters student at the Polytechnic University of Hong Kong
Shu Zhou
Research Assistant
Now a Ph.D student at the University of Edinburgh